MINI-GEMINI: Nanopore up and running @ IST

Nanopore sequencing works a bit like threading a string through a tiny sensor. In this method the DNA strand passes the small nanopores and as each nucleotide moves through the pore, it causes a small change in an electrical signal. The connected computer device translates the recovered signal change into a base and, consequently, in a DNA sequence. One big advantage of nanopore sequencing is that it can read DNA in real time and with simple and portable devices. Leveraging this, the Pedagogical Innovation Project MINI-GEMINI, awarded by the Pedagogical Council of IST and led by Professor Nuno Mira with the strong support of Diogo Santos and Teresa Ferreira students, will implement real time genome sequencing in Genomics-linked classes (Functional and Comparative Genomics and Functional Genomics and Bioinformatics). Nanopore-based sequencing will also boost research of our Master and PhD students, often needing long-read sequencing to get better genome reconstructions.
