Tiago Fernandes, a professor at Técnico, comments on the importance of the work awarded the Nobel Prize in Physiology or Medicine 2025.

“These discoveries have opened up a new research field and allowed for a better understanding of autoimmune diseases and cancer, and have already inspired treatments currently in clinical trials”. Tiago Fernandes, a professor at Técnico and researcher at the Institute for Bioengineering and Biosciences (iBB), comments on the implications of the work carried out by Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi, who were awarded the Nobel Prize in Physiology or Medicine 2025. “The Nobel Prize is fully justified. Before this research, it was not understood why some individuals developed serious autoimmune diseases”, he adds.

Tiago Fernandes answers some questions about the work awarded this year by the Karolinska Institute. See more.