Inhalable N-Acetylcysteine-loaded Lactose-coated PLGA Nanoparticles for Tuberculosis Treatment

This study presents a novel strategy to treat pulmonary tuberculosis using inhalable polymer nanoparticles.

The paper highlights:

  • A dry powder formulation for deep lung delivery
  • Controlled and sustained release of N-acetylcysteine (NAC)
  • Improved lung deposition and particle flowability
  • A superior antibacterial activity against Mycobacterium tuberculosis

This work is the result of an international collaboration, aiming to improve tuberculosis therapy with more effective and patient-friendly solutions.

We extend our congratulations to all the authors for their contribution to this high-impact research. See more.