Inhalable N-Acetylcysteine-loaded Lactose-coated PLGA Nanoparticles for Tuberculosis Treatment

This study presents a novel strategy to treat pulmonary tuberculosis using inhalable polymer nanoparticles.
The paper highlights:
- A dry powder formulation for deep lung delivery
- Controlled and sustained release of N-acetylcysteine (NAC)
- Improved lung deposition and particle flowability
- A superior antibacterial activity against Mycobacterium tuberculosis
This work is the result of an international collaboration, aiming to improve tuberculosis therapy with more effective and patient-friendly solutions.
We extend our congratulations to all the authors for their contribution to this high-impact research. See more.