Each person's brain has a unique pattern of connections, like a fingerprint. Migraine is cyclic, having several phases that may change how brain networks interact. In this study, we proposed a novel framework to explore how these brain fingerprints shift throughout the migraine cycle and when migraine patients' patterns become more similar to each other and different from healthy individuals. Our approach detects subtle changes that traditional methods often miss, bringing us closer to identifying a biomarker for migraine-related brain instability. To our knowledge, this represents the first case-control longitudinal functional neuroimaging study across the whole migraine cycle. (98/100). See more.