Diffusion tensor imaging studies examining white matter (WM) in migraine patients previously overlooked the potential influence of FW partial volume effects. Correcting FW effects could offer a clearer understanding of WM changes in migraine. Comparisons between control subjects and migraine patients revealed significantly lower axial diffusivity, with and without FW correction, altered FW values in migraine patients in some WM tracts and MD changes only after FW correction. These findings suggest WM alterations in these migraine patients in comparison with controls, in accordance with other migraine studies. These differences might point to inflammatory processes in migraine related to cellular swelling. (100/100). See more.